Arhgef7 conditional Knockout mouse

Target

Gene symbol :

Arhgef7

NCBI gene ID :

54126

Gene full name :

Rho guanine nucleotide exchange factor 7

Synonym :

β-Pix, Cool-1

Protein function

Protein name :

β-Pix

Activates Rac/Cdc42 GTPases; regulates cytoskeleton and synaptic development

Expected phenotype

Neuronal migration and spine morphology defects

Human disease relevance

Involved in neurological disorders and intellectual disability

Model applications

Synapse and neuronal development models

Keywords:

GEF, Rho signaling, Cytoskeleton

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Arhgef7

conditional Knockout mouse

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