Arid4a conditional Knockout mouse

Target

Gene symbol :

Arid4a

NCBI gene ID :

238247

Gene full name :

AT-rich interaction domain 4A

Synonym :

Rbp1-like, Rbp1l

Protein function

Protein name :

AT-rich interactive domain-containing protein 4A

Transcriptional corepressor; interacts with RB1; regulates chromatin remodeling

Expected phenotype

KO mice show growth retardation and increased apoptosis

Human disease relevance

Implicated in cancer and cell cycle regulation

Model applications

Studied in epigenetic silencing and tumor suppression

Keywords:

Chromatin, RB1, Transcriptional repression, Epigenetics

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Arid4a

conditional Knockout mouse

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