Arpc1b conditional Knockout mouse

Target

Gene symbol :

Arpc1b

NCBI gene ID :

11867

Gene full name :

Actin-related protein 2/3 complex subunit 1B

Synonym :

Arp2/3 subunit p41

Protein function

Protein name :

ARPC1B

Part of Arp2/3 complex controlling actin polymerization and cell migration.

Expected phenotype

Impaired immune synapse, thrombocytopenia

Human disease relevance

Linked to immunodeficiency and platelet disorders

Model applications

Cytoskeleton remodeling, immune cell function

Keywords:

Actin polymerization, Immunity, Arp2/3 complex

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Arpc1b

conditional Knockout mouse

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