Arpc3 conditional Knockout mouse

Target

Gene symbol :

Arpc3

NCBI gene ID :

56378

Gene full name :

Actin-related protein 2/3 complex subunit 3

Synonym :

Arc p21 protein 3

Protein function

Protein name :

ARPC3

Contributes to Arp2/3 complex; nucleates branched actin filaments for cell motility

Expected phenotype

Impaired migration and cytoskeleton defects

Human disease relevance

Linked to microglial dysfunction and intellectual disability-associated anomalies

Model applications

Cytoskeleton and motility models

Keywords:

Actin nucleation, Motility, Cytoskeleton

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Arpc3

conditional Knockout mouse

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