Target

Gene symbol :  
Asns
NCBI gene ID :  
27053
Gene full name :  
Asparagine synthetase (glutamine-hydrolyzing)
Synonym :  
ASNSD, TS11

Protein function

Protein name :  
ASNS
Catalyzes asparagine synthesis; also involved in tumor resistance to L-asparaginase

Expected phenotype

Brain development defects, memory impairment

Human disease relevance

Deficiency causes ASNS deficiency; also linked to chemotherapy resistance

Model applications

Metabolism, oncology, neurological models

Keywords:

Amino acid metabolism, Neurodevelopment, Cancer

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Asns

conditional Knockout mouse

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