Aspa conditional Knockout mouse

Target

Gene symbol :

Aspa

NCBI gene ID :

11484

Gene full name :

Aspartoacylase

Synonym :

Aspartoacylase

Protein function

Protein name :

ASPA

Hydrolyzes N-acetylaspartate (NAA); essential for myelin lipid synthesis.

Expected phenotype

Demyelination, tremors, reduced NAA degradation

Human disease relevance

Mutations cause Canavan disease

Model applications

Leukodystrophy modeling, myelination studies

Keywords:

NAA metabolism, Canavan disease, Myelin

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Aspa

conditional Knockout mouse

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