Target

Gene symbol :  
Aspa
NCBI gene ID :  
11484
Gene full name :  
Aspartoacylase
Synonym :  
Aspartoacylase

Protein function

Protein name :  
ASPA
Hydrolyzes N-acetylaspartate (NAA); essential for myelin lipid synthesis.

Expected phenotype

Demyelination, tremors, reduced NAA degradation

Human disease relevance

Mutations cause Canavan disease

Model applications

Leukodystrophy modeling, myelination studies

Keywords:

NAA metabolism, Canavan disease, Myelin

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Aspa

conditional Knockout mouse

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