Atl2 conditional Knockout mouse

Target

Gene symbol :

Atl2

NCBI gene ID :

56298

Gene full name :

Atlastin GTPase 2

Synonym :

Atlastin-2, SPG3A-like 2

Protein function

Protein name :

ATL2

ER membrane fusion GTPase that maintains ER network morphology

Expected phenotype

ER morphology defects, neurological issues

Human disease relevance

Implicated in ER stress diseases and hereditary spastic paraplegia-like mechanisms

Model applications

Neurodegeneration and ER morphology models

Keywords:

GTPase, ER-shaping, Fusion

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Atl2

conditional Knockout mouse

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