Target

Gene symbol :  
Babam2
NCBI gene ID :  
107976
Gene full name :  
BRISC and BRCA1 A complex member 2
Synonym :  
MERIT40, NBA1

Protein function

Protein name :  
MERIT40
Regulates BRCA1 recruitment and DNA double-strand break repair

Expected phenotype

Knockouts impair DNA repair; increase sensitivity to DNA damage

Human disease relevance

Involved in breast cancer and genomic stability maintenance

Model applications

Studied in DNA repair, BRCA1 complex, and tumor suppression

Keywords:

BRCA1, DNA repair, DSB repair, Tumor suppressor

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Babam2

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe