Target

Gene symbol :  
Bach2
NCBI gene ID :  
12014
Gene full name :  
BTB domain and CNC homolog 2
Synonym :  
BTB and CNC homology 2

Protein function

Protein name :  
BACH2
Transcription factor regulating immune cell differentiation and tolerance.

Expected phenotype

Autoimmunity, impaired memory T cells

Human disease relevance

Linked to type 1 diabetes, SLE, and cancer

Model applications

Immunoregulation, T and B cell biology

Keywords:

Transcription factor, Autoimmunity, B cell

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Bach2

conditional Knockout mouse

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