Bach2 conditional Knockout mouse

Target

Gene symbol :

Bach2

NCBI gene ID :

12014

Gene full name :

BTB domain and CNC homolog 2

Synonym :

BTB and CNC homology 2

Protein function

Protein name :

BACH2

Transcription factor regulating immune cell differentiation and tolerance.

Expected phenotype

Autoimmunity, impaired memory T cells

Human disease relevance

Linked to type 1 diabetes, SLE, and cancer

Model applications

Immunoregulation, T and B cell biology

Keywords:

Transcription factor, Autoimmunity, B cell

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Bach2

conditional Knockout mouse

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