Bap1 conditional Knockout mouse

Target

Gene symbol :

Bap1

NCBI gene ID :

104416

Gene full name :

BRCA1-associated protein 1

Synonym :

Uchbp

Protein function

Protein name :

Ubiquitin carboxyl-terminal hydrolase BAP1

Deubiquitinating enzyme; involved in chromatin remodeling, cell cycle, and tumor suppression

Expected phenotype

Knockouts show embryonic lethality and tumor predisposition

Human disease relevance

Mutations linked to mesothelioma, uveal melanoma, and renal cancer

Model applications

Widely used in cancer biology and epigenetic regulation studies

Keywords:

Deubiquitinase, Tumor suppressor, BRCA1, Chromatin remodeling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Bap1

conditional Knockout mouse

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