Target

Gene symbol :  
Bbs5
NCBI gene ID :  
72569
Gene full name :  
Bardet-Biedl syndrome 5
Synonym :  
BB5

Protein function

Protein name :  
Bardet-Biedl syndrome 5 protein
Part of the BBSome complex; regulates ciliary transport and signaling

Expected phenotype

Knockout causes obesity, retinal degeneration, and male infertility

Human disease relevance

Causative gene in Bardet-Biedl syndrome (ciliopathy)

Model applications

Used in cilia biology, retinal disease, and obesity research

Keywords:

Cilia, BBSome, Obesity, Retinal degeneration

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Bbs5

conditional Knockout mouse

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Easy access to models

Models with certified health status from professional breeders in US and Europe