Bola3 conditional Knockout mouse

Target

Gene symbol :

Bola3

NCBI gene ID :

78653

Gene full name :

BolA family member 3

Synonym :

1810056O20Rik

Protein function

Protein name :

BolA-like protein 3

Mitochondrial Fe‑S cluster assembly factor; supports lipoylation and oxidative metabolism

Expected phenotype

Knockout causes mitochondrial dysfunction and early growth defects

Human disease relevance

Mutations cause multiple mitochondrial dysfunction syndrome 2

Model applications

Model for mitochondrial Fe‑S biogenesis and metabolic disease

Keywords:

Mitochondria, Fe‑S cluster, Lipoylation, Metabolic disorder

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Bola3

conditional Knockout mouse

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