Brk1 conditional Knockout mouse

Target

Gene symbol :

Brk1

NCBI gene ID :

101314

Gene full name :

BRICK1, SCAR/WAVE complex subunit

Synonym :

HSPC300, C3orf10

Protein function

Protein name :

BRK1

Regulates actin cytoskeleton and lamellipodia formation via the WAVE complex.

Expected phenotype

Defects in cell migration and cytoskeletal dynamics

Human disease relevance

Linked to immune cell motility and cancer cell invasion

Model applications

Actin regulation, WAVE complex, cell motility

Keywords:

Cytoskeleton, WAVE, Actin remodeling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Brk1

conditional Knockout mouse

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