Target

Gene symbol :  
Cant1
NCBI gene ID :  
76025
Gene full name :  
Calcium activated nucleotidase 1
Synonym :  
SHAPY

Protein function

Protein name :  
Soluble calcium-activated nucleotidase 1
Hydrolyzes UDP; involved in proteoglycan biosynthesis

Expected phenotype

Knockouts show dwarfism and cartilage matrix defects

Human disease relevance

Mutations cause Desbuquois dysplasia type 1

Model applications

Studied in skeletal dysplasia and glycosylation pathways

Keywords:

Glycosylation, Proteoglycan, Cartilage, Nucleotidase

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cant1

conditional Knockout mouse

Get in touch about

Let us know how can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe