Cant1 conditional Knockout mouse

Target

Gene symbol :

Cant1

NCBI gene ID :

76025

Gene full name :

Calcium activated nucleotidase 1

Synonym :

SHAPY

Protein function

Protein name :

Soluble calcium-activated nucleotidase 1

Hydrolyzes UDP; involved in proteoglycan biosynthesis

Expected phenotype

Knockouts show dwarfism and cartilage matrix defects

Human disease relevance

Mutations cause Desbuquois dysplasia type 1

Model applications

Studied in skeletal dysplasia and glycosylation pathways

Keywords:

Glycosylation, Proteoglycan, Cartilage, Nucleotidase

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cant1

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe