Target

Gene symbol :  
Casz1
NCBI gene ID :  
69743
Gene full name :  
Castor zinc finger 1
Synonym :  
Castor, Zfp113

Protein function

Protein name :  
Zinc finger protein CASZ1
Transcription factor involved in heart and retinal development; regulates cell fate

Expected phenotype

Knockout results in embryonic lethality; critical for cardiac morphogenesis

Human disease relevance

Associated with neuroblastoma and congenital heart defects

Model applications

Used in cardiovascular development, cancer, and neurogenesis research

Keywords:

Transcription factor, Heart, Retina, Neuroblastoma

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Casz1

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe