Cdk5rap2 conditional Knockout mouse

Target

Gene symbol :

Cdk5rap2

NCBI gene ID :

214444

Gene full name :

CDK5 regulatory subunit associated protein 2

Synonym :

Cep215, MCHP

Protein function

Protein name :

CDK5 regulatory subunit-associated protein 2

Centrosomal protein regulating microtubule organization and spindle orientation

Expected phenotype

Knockouts show microcephaly, abnormal centrosomes, and defective brain development

Human disease relevance

Mutations cause autosomal recessive primary microcephaly

Model applications

Studied in neurodevelopment and centrosome function

Keywords:

Microcephaly, Centrosome, Brain development, Spindle orientation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cdk5rap2

conditional Knockout mouse

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