Cdkn2a conditional Knockout mouse

Target

Gene symbol :

Cdkn2a

NCBI gene ID :

12578

Gene full name :

Cyclin-dependent kinase inhibitor 2A

Synonym :

p16Ink4a, p19Arf

Protein function

Protein name :

CDKN2A

Tumor suppressor gene encoding p16 and p19; regulates cell cycle and senescence.

Expected phenotype

Enhanced proliferation, tumor susceptibility

Human disease relevance

Mutated in many cancers (e.g., melanoma, pancreatic)

Model applications

Cell cycle control, cancer models

Keywords:

Tumor suppressor, Cell cycle, p16

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cdkn2a

conditional Knockout mouse

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