Cep41 conditional Knockout mouse

Target

Gene symbol :

Cep41

NCBI gene ID :

83922

Gene full name :

Centrosomal protein 41

Synonym :

1700017E11Rik, 2810431D15Rik, Tsga14

Protein function

Protein name :

CEP41

Required for tubulin glutamylation and cilia function in centriole/cilium biogenesis

Expected phenotype

Knockouts show ciliopathy-like phenotypes, early lethality

Human disease relevance

Mutations cause Joubert syndrome type 15 in humans

Model applications

Used in cilia biology, centrosome function, and developmental studies

Keywords:

Ciliogenesis, Centrosome, Tubulin glutamylation, Joubert syndrome

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cep41

conditional Knockout mouse

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