Target

Gene symbol :  
Cers1
NCBI gene ID :  
93898
Gene full name :  
Ceramide synthase 1
Synonym :  
Lass1

Protein function

Protein name :  
Ceramide synthase 1
Synthesizes C18-ceramides; involved in sphingolipid metabolism and neuronal function

Expected phenotype

Knockouts show altered brain lipid composition and neurological defects

Human disease relevance

Associated with progressive myoclonic epilepsy and neurodegeneration

Model applications

Studied in sphingolipid biology, neurology, and apoptosis

Keywords:

Ceramide, Sphingolipid, Neurodegeneration, Lipid metabolism

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cers1

conditional Knockout mouse

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