Chmp4c conditional Knockout mouse

Target

Gene symbol :

Chmp4c

NCBI gene ID :

66371

Gene full name :

CHMP4 homolog C (charged multivesicular body protein 4C)

Synonym :

Charged multivesicular body protein 4C, CHMP4C

Protein function

Protein name :

CHMP4C

ESCRT-III complex subunit; mediates membrane remodeling during cytokinesis and endosomal sorting

Expected phenotype

Cytokinesis defects, endosomal trafficking errors

Human disease relevance

Linked to tumor growth and viral budding

Model applications

Cytokinesis and membrane remodeling models

Keywords:

ESCRT, Cytokinesis, Vesicle trafficking

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Chmp4c

conditional Knockout mouse

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