Target

Gene symbol :  
Chrna7
NCBI gene ID :  
11441
Gene full name :  
Cholinergic receptor nicotinic alpha 7 subunit
Synonym :  
Nicotinic receptor α7

Protein function

Protein name :  
α7 nAChR
Ligand-gated ion channel mediating fast synaptic transmission.

Expected phenotype

Altered cognition, seizures

Human disease relevance

Linked to schizophrenia, epilepsy, Alzheimer’s

Model applications

CNS signaling, neuropsychiatric research

Keywords:

Nicotinic receptor, Synapse, Neurotransmission

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Chrna7

conditional Knockout mouse

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