Clcn3 conditional Knockout mouse

Target

Gene symbol :

Clcn3

NCBI gene ID :

12725

Gene full name :

Chloride voltage-gated channel 3

Synonym :

Clc3

Protein function

Protein name :

Chloride channel protein 3

Voltage-gated chloride channel involved in endosomal acidification and neuronal excitability

Expected phenotype

Neurodegeneration, hippocampal defects, altered synaptic transmission

Human disease relevance

Neurodegenerative disorders, epilepsy

Model applications

Neurobiology and ion channel models

Keywords:

chloride channel, endosomes, neuronal signaling

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Clcn3

conditional Knockout mouse

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