Target

Gene symbol :  
Clpp
NCBI gene ID :  
53895
Gene full name :  
Caseinolytic peptidase P mitochondrial
Synonym :  
CLP1, CLPP1

Protein function

Protein name :  
CLPP
ATP-dependent mitochondrial protease; processes misfolded proteins

Expected phenotype

Perinatal lethality, mitochondrial dysfunction

Human disease relevance

Recessive Perrault syndrome, mitochondrial disorders

Model applications

Mitochondrial stress and proteostasis models

Keywords:

Protease, Mitochondria, Protein quality control

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Clpp

conditional Knockout mouse

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