Coq4 conditional Knockout mouse

Target

Gene symbol :

Coq4

NCBI gene ID :

227683

Gene full name :

Coenzyme Q4 homolog

Synonym :

—

Protein function

Protein name :

Coenzyme Q biosynthesis protein Coq4

Central role in biosynthesis of coenzyme Q (ubiquinone) in mitochondria

Expected phenotype

KO is embryonically lethal due to mitochondrial failure

Human disease relevance

Mutations cause CoQ10 deficiency syndromes in humans

Model applications

Used in mitochondrial and metabolic disease research

Keywords:

Coenzyme Q, Mitochondria, Metabolism, Ubiquinone biosynthesis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Coq4

conditional Knockout mouse

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