Target

Gene symbol :  
Cpsf3
NCBI gene ID :  
54451
Gene full name :  
Cleavage and polyadenylation specific factor subunit 3
Synonym :  
CPSF-3, CPSF III subunit 3

Protein function

Protein name :  
CPSF3
Catalytic endonuclease for pre-mRNA 3′ end processing

Expected phenotype

mRNA processing defects, embryonic lethality

Human disease relevance

Implicates in mRNA 3′ end formation disorders

Model applications

RNA processing and transcriptome stability

Keywords:

mRNA 3′ cleavage, RNA processing

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cpsf3

conditional Knockout mouse

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