Target

Gene symbol :  
Crls1
NCBI gene ID :  
66586
Gene full name :  
Cardiolipin synthase
Synonym :  
TMEM274, Cardiolipin synthase

Protein function

Protein name :  
CRLS1
Catalyzes the synthesis of cardiolipin in the mitochondrial inner membrane

Expected phenotype

Altered phospholipid composition, mitochondrial dysfunction

Human disease relevance

Linked to Barth syndrome-like lipid disorders

Model applications

Mitochondrial lipid synthesis models

Keywords:

Cardiolipin, Mitochondria, Lipid metabolism

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Crls1

conditional Knockout mouse

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