Target

Gene symbol :  
Crtl1
NCBI gene ID :  
12950
Gene full name :  
Hyaluronan and proteoglycan link protein 1
Synonym :  
HAPLN1, cartilage link protein 1

Protein function

Protein name :  
HAPLN1
Stabilizes extracellular matrix by linking hyaluronan to proteoglycans.

Expected phenotype

Cartilage abnormalities

Human disease relevance

Implicated in joint disease and skeletal defects

Model applications

Cartilage structure, osteoarthritis

Keywords:

ECM, Hyaluronan, Cartilage

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Crtl1

conditional Knockout mouse

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