Target

Gene symbol :  
Csf2ra
NCBI gene ID :  
12982
Gene full name :  
Colony stimulating factor 2 receptor alpha
Synonym :  
GM-CSF receptor alpha

Protein function

Protein name :  
CSF2RA
Receptor for GM-CSF; essential for myeloid lineage cell development.

Expected phenotype

Impaired macrophage and granulocyte function

Human disease relevance

Linked to pulmonary alveolar proteinosis (PAP)

Model applications

Hematopoiesis, alveolar macrophage models

Keywords:

GM-CSF, Myeloid, Immune cell differentiation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Csf2ra

conditional Knockout mouse

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