Ctnnbip1 conditional Knockout mouse

Target

Gene symbol :

Ctnnbip1

NCBI gene ID :

67087

Gene full name :

Catenin β–interacting protein 1

Synonym :

ICAT

Protein function

Protein name :

CTNNBIP1

Inhibits β–catenin–TCF interaction; regulates Wnt signaling

Expected phenotype

Wnt overactivation, developmental/WT defects

Human disease relevance

Acts as tumor suppressor; implicated in colorectal cancer

Model applications

Wnt pathway and developmental disease models

Keywords:

Wnt inhibitor, Development, Cancer

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ctnnbip1

conditional Knockout mouse

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