Cul7 conditional Knockout mouse

Target

Gene symbol :

Cul7

NCBI gene ID :

66515

Gene full name :

Cullin 7

Synonym :

Cullin 7, p185, 3MC syndrome protein

Protein function

Protein name :

CUL7

E3 ubiquitin ligase scaffold involved in growth and metabolism regulation

Expected phenotype

Growth retardation, skeletal defects

Human disease relevance

Mutations cause 3M syndrome; linked to cancer prevention

Model applications

Ubiquitination, growth, and developmental models

Keywords:

Ubiquitin ligase, Growth, 3M syndrome

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cul7

conditional Knockout mouse

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