Target

Gene symbol :  
Cyfip2
NCBI gene ID :  
76884
Gene full name :  
Cytoplasmic FMR1 interacting protein 2
Synonym :  
PIR121L

Protein function

Protein name :  
Cytoplasmic FMR1-interacting protein 2
Interacts with FMRP; regulates actin remodeling and synaptic plasticity

Expected phenotype

Knockouts display altered behavior and brain development

Human disease relevance

Implicated in neurodevelopmental and neuropsychiatric disorders

Model applications

Used in neuroscience and synaptic function models

Keywords:

Actin cytoskeleton, FMRP, Synapse, Neurodevelopment

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cyfip2

conditional Knockout mouse

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