Target

Gene symbol :  
Daam1
NCBI gene ID :  
208846
Gene full name :  
Dishevelled associated activator of morphogenesis 1
Synonym :  

Protein function

Protein name :  
DAAM1 protein
Formin family protein linking Wnt/PCP signaling to actin cytoskeleton dynamics

Expected phenotype

Knockouts affect gastrulation, neural tube closure, and cardiac morphogenesis

Human disease relevance

Involved in developmental disorders and cancer cell migration

Model applications

Studied in cytoskeleton remodeling and Wnt signaling

Keywords:

Wnt signaling, Formin, Actin dynamics, Morphogenesis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Daam1

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe