Target

Gene symbol :  
Dctn1
NCBI gene ID :  
13191
Gene full name :  
Dynactin subunit 1
Synonym :  
p150-glued, DCTN1

Protein function

Protein name :  
DCTN1
Anchors cytoplasmic dynein to cargo, essential for microtubule-based transport and mitosis.

Expected phenotype

Neuronal transport defects

Human disease relevance

Mutations linked to ALS and Perry syndrome

Model applications

Axonal transport, neurodegeneration

Keywords:

Dynactin, Microtubules, Neuron

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Dctn1

conditional Knockout mouse

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