Target

Gene symbol :  
Dcx
NCBI gene ID :  
13193
Gene full name :  
Doublecortin
Synonym :  
Doublecortin, Doublin

Protein function

Protein name :  
DCX
Microtubule-associated protein critical for neuronal migration during development.

Expected phenotype

Lissencephaly-like cortex structure

Human disease relevance

Mutated in lissencephaly, subcortical band heterotopia

Model applications

Brain development, cortical neuron migration

Keywords:

Neurodevelopment, Microtubule, Migration

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Dcx

conditional Knockout mouse

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