Ddhd2 conditional Knockout mouse

Target

Gene symbol :

Ddhd2

NCBI gene ID :

72108

Gene full name :

DDHD domain containing 2

Synonym :

HSPC129

Protein function

Protein name :

Phospholipase DDHD2

Phospholipase involved in lipid metabolism and Golgi/ER membrane dynamics

Expected phenotype

Knockouts show neurodegeneration and lipid droplet accumulation

Human disease relevance

Mutations linked to hereditary spastic paraplegia (SPG54)

Model applications

Used in neurodegeneration and lipid metabolism models

Keywords:

Phospholipase, Lipid droplets, Neurodegeneration, SPG

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ddhd2

conditional Knockout mouse

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