Target

Gene symbol :  
Deptor
NCBI gene ID :  
97998
Gene full name :  
DEP domain containing MTOR-interacting protein
Synonym :  
DEPDC6

Protein function

Protein name :  
DEP domain-containing mTOR-interacting protein
Negative regulator of mTORC1 and mTORC2; modulates metabolism and cell growth

Expected phenotype

Alters mTOR signaling; affects insulin sensitivity and growth

Human disease relevance

Implicated in multiple myeloma and metabolic diseases

Model applications

Used in cancer, metabolism, and mTOR pathway studies

Keywords:

mTOR, Metabolism, Cancer, Signal transduction

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Deptor

conditional Knockout mouse

Get in touch about

Let us know how can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe