Target

Gene symbol :  
Dlg4
NCBI gene ID :  
13385
Gene full name :  
Discs large MAGUK scaffold protein 4
Synonym :  
PSD95, SAP90

Protein function

Protein name :  
PSD-95
Synaptic scaffolding protein critical for excitatory synapse function in CNS.

Expected phenotype

Synaptic plasticity defects, altered behavior

Human disease relevance

Implicated in autism, schizophrenia, and epilepsy

Model applications

Neurodevelopment, synaptic modeling

Keywords:

Synapse, Neurodevelopment, PSD proteins

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Dlg4

conditional Knockout mouse

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