Target

Gene symbol :  
Dnmt3l
NCBI gene ID :  
54427
Gene full name :  
DNA methyltransferase 3-like
Synonym :  
DNMT3-L, DNMT3-like

Protein function

Protein name :  
DNMT3L
Noncatalytic regulator of de novo DNA methylation during germ cell development

Expected phenotype

Fertility defects, epigenetic irregularities

Human disease relevance

Altered imprinting and fertility issues

Model applications

Epigenetics and germline development models

Keywords:

DNA methylation, Epigenetics

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Dnmt3l

conditional Knockout mouse

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