Dock10 conditional Knockout mouse

Target

Gene symbol :

Dock10

NCBI gene ID :

210293

Gene full name :

Dedicator of cytokinesis 10

Synonym :

—

Protein function

Protein name :

DOCK10 protein

Atypical guanine nucleotide exchange factor (GEF) for Rac1 and Cdc42

Expected phenotype

Functionally linked to cytoskeletal rearrangements in immune cells

Human disease relevance

Overexpressed in B-cell malignancies and activated T cells

Model applications

Studied in lymphocyte function and cytoskeleton dynamics

Keywords:

GEF, Rho GTPases, Immune signaling, Cytoskeleton

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Dock10

conditional Knockout mouse

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