Eaf1 conditional Knockout mouse

Target

Gene symbol :

Eaf1

NCBI gene ID :

74427

Gene full name :

ELL-associated factor 1

Synonym :

ELL-associated factor 1

Protein function

Protein name :

ELL-associated factor 1

Regulates transcription elongation by RNA polymerase II; chromatin remodeling partner

Expected phenotype

Limited phenotype data; essential in transcriptional regulation

Human disease relevance

Implicated in leukemia via fusion with MLL in humans

Model applications

Studied in transcription elongation and leukemogenesis

Keywords:

Transcription, Elongation, RNA Pol II, Leukemia

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Eaf1

conditional Knockout mouse

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