Target

Gene symbol :  
Eomes
NCBI gene ID :  
13813
Gene full name :  
Eomesodermin
Synonym :  
Tbr2, eomesodermin

Protein function

Protein name :  
EOMES
T-box transcription factor crucial for mesoderm formation and cytotoxic T-cell development.

Expected phenotype

Embryonic lethality, defective T-cell development

Human disease relevance

Relevant in developmental biology and cancer

Model applications

Embryogenesis, immune function

Keywords:

T-box, Development, CD8+ T cells

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Eomes

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe