Ercc2 conditional Knockout mouse

Target

Gene symbol :

Ercc2

NCBI gene ID :

13871

Gene full name :

Excision repair cross-complementation group 2

Synonym :

Xpd, Rad3

Protein function

Protein name :

ERCC2

DNA helicase involved in nucleotide excision repair and transcription-coupled repair.

Expected phenotype

DNA repair deficiency, UV sensitivity

Human disease relevance

Associated with xeroderma pigmentosum, cancer risk

Model applications

DNA repair, transcription-coupled repair

Keywords:

Helicase, NER, Genome stability

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ercc2

conditional Knockout mouse

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