Esco2 conditional Knockout mouse

Target

Gene symbol :

Esco2

NCBI gene ID :

71988

Gene full name :

Establishment of sister chromatid cohesion N-acetyltransferase 2

Synonym :

Eco1L, Efo2

Protein function

Protein name :

N-acetyltransferase ESCO2

Catalyzes acetylation of cohesin subunits; essential for sister chromatid cohesion

Expected phenotype

Knockout causes embryonic lethality and defective mitosis

Human disease relevance

Mutations cause Roberts syndrome

Model applications

Used in studies of chromatid cohesion and developmental disorders

Keywords:

Cohesion, Acetyltransferase, Roberts syndrome, Cell cycle

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Esco2

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe