Espn conditional Knockout mouse

Target

Gene symbol :

Espn

NCBI gene ID :

56226

Gene full name :

Espin

Synonym :

Espin, BLL, ESPN-A/B/C

Protein function

Protein name :

ESPN

Actin-bundling protein critical to stereocilia length and orientation in hair cells

Expected phenotype

Deafness, abnormal stereocilia structure

Human disease relevance

Mutations cause autosomal recessive and dominant deafness

Model applications

Hearing and hair-cell stereocilia models

Keywords:

Actin-bundling, Sensory, Deafness

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Espn

conditional Knockout mouse

Get in touch about

Let us know how can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe