Target

Gene symbol :  
F2
NCBI gene ID :  
14061
Gene full name :  
Coagulation factor II
Synonym :  
Coagulation factor II, Prothrombin

Protein function

Protein name :  
F2 / Prothrombin
Precursor to thrombin, a key enzyme in blood coagulation cascade.

Expected phenotype

Bleeding disorders, delayed clotting

Human disease relevance

Deficiency causes hypoprothrombinemia

Model applications

Hemostasis, coagulation studies

Keywords:

Coagulation, Serine protease, Thrombin

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

F2

conditional Knockout mouse

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