Fbxl7 conditional Knockout mouse

Target

Gene symbol :

Fbxl7

NCBI gene ID :

448987

Gene full name :

F-box and leucine-rich repeat protein 7

Synonym :

—

Protein function

Protein name :

F-box/LRR-repeat protein 7

Component of SCF ubiquitin ligase complex; involved in targeting proteins for degradation

Expected phenotype

Affects apoptosis and epithelial cell polarity in vitro

Human disease relevance

Downregulated in some human cancers

Model applications

Model for protein degradation and tumor suppression

Keywords:

Ubiquitin ligase, SCF complex, Apoptosis, Cancer

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Fbxl7

conditional Knockout mouse

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