Fbxo11 conditional Knockout mouse

Target

Gene symbol :

Fbxo11

NCBI gene ID :

225055

Gene full name :

F-box protein 11

Synonym :

Prmt3os

Protein function

Protein name :

F-box only protein 11

E3 ubiquitin ligase component; regulates TGF-β and p53 pathways

Expected phenotype

KO mice show developmental defects and immune dysregulation

Human disease relevance

Associated with B-cell lymphoma and developmental syndromes

Model applications

Studied in ubiquitination, development, and immune signaling

Keywords:

F-box, Ubiquitin ligase, TGF-β, Immune regulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Fbxo11

conditional Knockout mouse

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