Target

Gene symbol :  
Fto
NCBI gene ID :  
26383
Gene full name :  
FTO alpha-ketoglutarate-dependent dioxygenase
Synonym :  
Fat mass and obesity-associated gene

Protein function

Protein name :  
FTO
RNA demethylase (m6A); regulates metabolism, energy homeostasis, and adipogenesis

Expected phenotype

Obesity, growth retardation, metabolic disturbances

Human disease relevance

Strongly linked to obesity, metabolic syndrome, neurodevelopmental issues

Model applications

Metabolism, epigenetics, energy homeostasis models

Keywords:

m6A demethylase, Metabolism, Obesity

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Fto

conditional Knockout mouse

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