Fyb conditional Knockout mouse

Target

Gene symbol :

Fyb

NCBI gene ID :

23880

Gene full name :

FYN-binding protein

Synonym :

ADAP, SLAP-130

Protein function

Protein name :

FYB

Adapter protein in T-cell receptor signaling and actin cytoskeleton organization

Expected phenotype

T-cell activation defects, impaired migration

Human disease relevance

Implicated in immune deficiency and autoimmunity

Model applications

T-cell signaling and immune response models

Keywords:

Adapter protein, T-cell activation, Cytoskeleton

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Fyb

conditional Knockout mouse

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