Target

Gene symbol :  
G6pc
NCBI gene ID :  
14377
Gene full name :  
Glucose-6-phosphatase, catalytic subunit
Synonym :  
G-6-Pase, G6pase

Protein function

Protein name :  
G6PC
Final enzyme in gluconeogenesis and glycogenolysis; converts G6P to glucose.

Expected phenotype

Hypoglycemia, hepatomegaly

Human disease relevance

Mutation causes glycogen storage disease type I (GSDI)

Model applications

Metabolic disease, liver function

Keywords:

Glucose metabolism, GSDI, Liver

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

G6pc

conditional Knockout mouse

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