G6pc conditional Knockout mouse

Target

Gene symbol :

G6pc

NCBI gene ID :

14377

Gene full name :

Glucose-6-phosphatase, catalytic subunit

Synonym :

G-6-Pase, G6pase

Protein function

Protein name :

G6PC

Final enzyme in gluconeogenesis and glycogenolysis; converts G6P to glucose.

Expected phenotype

Hypoglycemia, hepatomegaly

Human disease relevance

Mutation causes glycogen storage disease type I (GSDI)

Model applications

Metabolic disease, liver function

Keywords:

Glucose metabolism, GSDI, Liver

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

G6pc

conditional Knockout mouse

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